Background

David Galas has had a mix of experience in business, government, and the academic world.  Prior to coming to help found the Keck Graduate Institute in Claremont, California, he served as president and chief scientific officer of Seattle-based Chiroscience R & D Inc., a company was formed through the acquisition of Darwin Molecular Corporation, which Dr. Galas co-founded.  He began his tenure at Darwin Molecular Corporation in 1993 as vice president of research and development.

Prior to this, Dr. Galas served as director for Health and Environmental Research at the U.S. Department of Energy's Office of Energy Research from 1990 to 1993, where he was responsible for all life sciences research funded by the Department, including the DOE component of the Human Genome Project.  Before his service in Washington, Dr. Galas was a professor of molecular biology at the University of Southern California. 

Dr. Galas' formal educational training was not in molecular biology, but in physics.  He received his undergraduate degree in physics at the University of California, Berkeley, and also received his Ph.D. in physics from the University of California.  He has also held posts at the University of Geneva, Switzerland, and the University of California's Lawrence Livermore Laboratory.  His broad research interests include several areas of molecular biology and human genetics, including transposable genetic elements, and the application of mathematical methods and new technologies in the life sciences. Dr. Galas is a member of many professional organizations, commissions and boards, including the Human Genome Organization, the National Academy of Sciences Research Council Board on Life Sciences and the Board of Governors of the National Center for Genome Resources.  Dr. Galas also serves on several corporate scientific advisory boards and boards of directors.  He has been a member of many federal and academic advisory groups including the national Biotechnology Policy Board, and the National Cancer Advisory Board.  He chaired the Biotechnology Research Subcommittee of the Federal Coordinating Council on Science and Technology for the Office of Science and Technology Policy.  He is also a member of the Policy Board of the Joint Genome Institute of the University of California, and the Editorial Board of the Journal of Computational Biology, the Journal of Bioinformatics & Computational Biology and Functional and Integrative Genomics.  He was a recipient, with five other scientists, of the Smithsonian, Platinum Technologies 1999 award for his early role in the international human genome project.

 

Research Interests

Current research interests focus on two areas.  The first is the development of new technologies for the amplification and analysis of nucleic acids.  This work is directed to enabling new methods for high throughput and accurate data acquisition needed to analyze a variety of biological systems, and to the development of new diagnostic techniques in medicine.  Our recent work in this area has led to a promising oligonucleotide amplification technology that is rapid, simple and accurate.  In collaboration with Ionian Technologies Inc. a company organized to commericalize this technology, we are developing new research tools and diagnostic applications. 

The second center interest area centers around the structures of biological networks and the analysis of their properties.  These studies have focused most recentlyon the statistical structures of complex biological networks, on the one hand, and the properties and prediction of gene regulatory and protein-protein interaction networks on the other.